
The Actinium-225 (Ac-225) PSMA Alpha Prostate Premium Program with PSMA PET/CT Scan is an advanced precision therapy developed for patients with metastatic, progressive, or treatment-resistant prostate cancer. This program integrates molecular imaging and targeted alpha therapy within a structured treatment pathway. Before therapy, a specialized PSMA PET/CT scan is performed at our hospital to assess PSMA receptor expression and evaluate the extent of disease. Treatment eligibility is determined based on this molecular imaging assessment, ensuring that only suitable patients proceed to Actinium-225 therapy. The treatment uses Actinium-225, a highly potent alpha-emitting isotope attached to a PSMA-targeting molecule that selectively binds to prostate cancer cells. Once internalized, Actinium-225 releases powerful radiation directly inside the cancer cell, destroying it from within. Because alpha radiation acts over an ultra-short distance, surrounding healthy tissue is largely protected while maintaining strong therapeutic intensity. This makes the therapy particularly valuable for advanced or resistant prostate cancer cases. The program is conducted under the medical leadership of Assoc. Prof. Dr. Kezban Berberoğlu, Director of Nuclear Medicine, who brings more than 20 years of experience in nuclear medicine and advanced molecular imaging, supported by international academic training in the United States. All treatments are administered in a specialized nuclear medicine environment under strict safety and monitoring protocols. The therapeutic compound is sourced through internationally regulated pharmaceutical supply channels, including certified medication suppliers in the United States, ensuring high manufacturing standards, quality control, and traceability. The treatment package includes nuclear medicine consultation, comprehensive laboratory testing, PSMA PET/CT imaging, renal evaluation when indicated, administration of Actinium-225 PSMA therapy, and structured medical follow-up. The recommended stay is approximately four days per treatment cycle, including arrival and departure, provided no significant side effects or unexpected medical events occur. If necessary, monitoring may be extended to ensure patient safety. Cost-efficient partner hotels are available near the hospital, offering daily shuttle service between the hotel and the medical center to ensure convenient and organized logistics throughout the treatment process.
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